What is the function of phospholipid N-methylation?
نویسندگان
چکیده
منابع مشابه
What is the function of phospholipid N-methylation?
Most if not all membrane functions are made possible by the unique composition of proteins and lipids in biological membranes. Although most biological membranes carry out similar functions, their composition varies largely (reviewed by Quinn, 1977). Thus, the protein/lipid ratio of rat plasma membranes can vary from 0.25 in myelin to 1.5 in the liver. The ratio cholesterol/phospholipid can als...
متن کاملWhat is the Real Cause of Glaucoma?
Introduction: The term glaucoma refers to a group of diseases that have a characteristic optic neuropathy with associated visual field loss in common. Intraocular pressure has been considered to be the only causal factor for glaucoma and the only factor that can be manipulated to alter the course of the disease. But considering high intraocular pressure as the only factor responsible for glauco...
متن کاملPlasma homocysteine is regulated by phospholipid methylation.
Mild hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Homocysteine, a non-protein amino acid, is formed from S-adenosylhomocysteine and partially secreted into plasma. A potential source for homocysteine is methylation of the lipid phosphatidylethanolamine to phosphatidylcholine by phosphatidylethanolamine N-methyltransferase in the liver. We show that mice that la...
متن کاملStimulation of phospholipid N-methylation by isoproterenol in rat hearts.
Phosphatidylethanolamine (PtdEtn) N-methyltransferase activities were studied in rat heart sarcolemmal and sarcoplasmic reticular fractions after a single intraperitoneal injection of isoproterenol (0.5-5.0 mg/kg). Three active sites (I, II, and III) for PtdEtn N-methylation were assayed by measurement of [3H]methyl group incorporation from 0.055, 10, and 150 microM S-adenosyl-L-[methyl-3H]meth...
متن کاملP-value: What is and what is not
The misinterpretation and misuse of p-value have been increasing for decades. In March 2016, the American Statistical Association released a statement to warn about the use and interpretation of p-value. In this study, we provided a definition and discussion of p-value and emphasized the importance of its accurate interpretation.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1983
ISSN: 0264-6021
DOI: 10.1042/bj2130001